Nandrolone decanoate
Deca-durabolin (nandrolone decanoate) is a small molecule pharmaceutical. Nandrolone decanoate was first approved as Nandrolone decanoate on 1983-09-28. It is used to treat anemia and breast neoplasms in the USA.
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New Drug Application (NDA)
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Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Nandrolone decanoate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| DECA-DURABOLIN | Woodward Pharma Services | N-013132 DISCN | 1986-06-12 | 3 products, RLD |
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FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| nandrolone decanoate | 2007-02-08 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| breast neoplasms | EFO_0003869 | D001943 | C50 |
| anemia | EFO_0004272 | D000740 | D64.9 |
Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
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HCPCS
Code | Description |
|---|---|
| J2320 | Injection, nandrolone decanoate, up to 50 mg |
Clinical
Clinical Trials
15 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypogonadism | D007006 | — | E23.0 | — | — | — | 2 | — | 2 |
| Femoracetabular impingement | D057925 | — | — | — | — | — | 1 | — | 1 |
| Hip osteoarthritis | D015207 | EFO_1000786 | M16 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Burns | D002056 | — | T30.0 | — | 2 | 2 | — | 1 | 3 |
| Aplastic anemia | D000741 | — | D61.9 | 1 | 1 | 1 | — | — | 2 |
| Motor activity | D009043 | EFO_0003940 | — | — | 1 | 1 | — | — | 1 |
| Hematologic diseases | D006402 | EFO_0005803 | D75.9 | — | — | 1 | — | — | 1 |
| Pancytopenia | D010198 | — | D61.81 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hip fractures | D006620 | EFO_0003964 | S72.00 | — | 1 | — | — | — | 1 |
| Idiopathic pulmonary fibrosis | D054990 | — | J84.112 | 1 | 1 | — | — | — | 1 |
| Bone marrow failure disorders | D000080983 | — | — | 1 | 1 | — | — | — | 1 |
| Telomere shortening | D059506 | — | — | 1 | 1 | — | — | — | 1 |
| Critical illness | D016638 | — | — | — | 1 | — | — | — | 1 |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | — | 1 | — | — | — | 1 |
| Sarcopenia | D055948 | EFO_1000653 | M62.84 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hiv infections | D015658 | EFO_0000764 | B20 | 1 | — | — | — | — | 1 |
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | 1 | — | — | — | — | 1 |
| Aids-related complex | D000386 | EFO_0007137 | B20 | 1 | — | — | — | — | 1 |
| Hiv wasting syndrome | D019247 | EFO_0007312 | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | — | — | — | — | 1 | 1 |
| Cachexia | D002100 | — | R64 | — | — | — | — | 1 | 1 |
| Muscular atrophy | D009133 | — | — | — | — | — | — | 1 | 1 |
| Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | — | — | — | — | 1 | 1 |
| Muscle weakness | D018908 | — | — | — | — | — | — | 1 | 1 |
| Heart arrest | D006323 | EFO_0009492 | I46 | — | — | — | — | 1 | 1 |
| Growth | D006128 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Nandrolone decanoate |
| INN | — |
| Description | Nandrolone decanoate is a steroid ester. |
| Classification | Small molecule |
| Drug class | androgens; steroids (not prednisolone derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCCCCCCCCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@]12C |
Identifiers
| PDB | — |
| CAS-ID | 360-70-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1200946 |
| ChEBI ID | 7467 |
| PubChem CID | 9677 |
| DrugBank | DB08804 |
| UNII ID | — |
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Safety
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201 adverse events reported
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